Ethanone, 1-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-
1-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]ethanone
CAS: 1173693-36-1
Molecular Formula: C11H9F2NO2
Ethanone, 1-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]- - Names and Identifiers
Ethanone, 1-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]- - Physico-chemical Properties
| Molecular Formula | C11H9F2NO2 |
| Molar Mass | 225.19 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Boling Point | 259.0±50.0 °C(Predicted) |
| Vapor Presure | 0.005-0.026Pa at 20-40℃ |
| Appearance | Solid |
Ethanone, 1-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]- - Introduction
1-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl] ethanone is an organic compound. The following is information on the nature, use and preparation of the compound:
Nature:
-Appearance: White or off-white crystalline powder.
-Molecular formula: C11H8F2N2O2.
-Molecular weight: 246.19g/mol.
-Melting point: 97-98 degrees Celsius.
Use:
- 1-[5-(2,6-difluorophenyl)-4,5-dihydro -1, 2-oxazol-3-yl] ethanone is an organic synthetic intermediate with broad-spectrum activity.
-It can be used to synthesize drugs, pesticides and other organic compounds.
Preparation Method:
Currently, for 1-[5-(2,6-difluorophenyl)-4,5-dihydro -1, the preparation methods of 2-oxazol-3-yl] ethanone are rarely reported in detail. But one possible method of preparation is synthesis by a ring-closing reaction:
1. First, an appropriate amount of 2,6-difluorobenzoic acid is reacted with an appropriate amine in the reaction system to obtain 2,6-difluorophenyl amide.
2. Then, under appropriate conditions, the 2,6-difluorophenyl amide and acetic anhydride ring reaction, the formation of 1-[5-(2,6-difluorophenyl)-4, 5-Dihydro-1, 2-oxazol-3-yl] ethanone.
It should be noted that this is only one possible preparation method, and the specific preparation conditions and reaction steps may vary depending on laboratory conditions and requirements. It is recommended to consult the relevant literature and patent information before operation.
Nature:
-Appearance: White or off-white crystalline powder.
-Molecular formula: C11H8F2N2O2.
-Molecular weight: 246.19g/mol.
-Melting point: 97-98 degrees Celsius.
Use:
- 1-[5-(2,6-difluorophenyl)-4,5-dihydro -1, 2-oxazol-3-yl] ethanone is an organic synthetic intermediate with broad-spectrum activity.
-It can be used to synthesize drugs, pesticides and other organic compounds.
Preparation Method:
Currently, for 1-[5-(2,6-difluorophenyl)-4,5-dihydro -1, the preparation methods of 2-oxazol-3-yl] ethanone are rarely reported in detail. But one possible method of preparation is synthesis by a ring-closing reaction:
1. First, an appropriate amount of 2,6-difluorobenzoic acid is reacted with an appropriate amine in the reaction system to obtain 2,6-difluorophenyl amide.
2. Then, under appropriate conditions, the 2,6-difluorophenyl amide and acetic anhydride ring reaction, the formation of 1-[5-(2,6-difluorophenyl)-4, 5-Dihydro-1, 2-oxazol-3-yl] ethanone.
It should be noted that this is only one possible preparation method, and the specific preparation conditions and reaction steps may vary depending on laboratory conditions and requirements. It is recommended to consult the relevant literature and patent information before operation.
Last Update：2024-04-09 21:01:54
![Ethanone, 1-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-](http://res.chembk.com/assets/str/2d/1/11/1173693-36-1.png)